Bullous pemphygoid of childhood.. Strep or bubonic herpes. Epidermolysis of the epidermis. Follicular papillary artery. Smooth pigment and endocarditis with intestinal dysfunction

Bullous pemphygoid of childhood:
It is a chronic bubonic disease in childhood. It is rare. Several names have been given to this disease, such as sputum falciparum in children, juvenile dermatitis, juvenile seborrheic spondylitis, and spondylitis.
Clinical manifestations:
- Large clusters that become much extended, usually affecting the genitals, buttocks and soles of the thighs. Most patients have lesions in the scalp, around the mouth and, less commonly, to the mucous membranes of the mouth.
Large, sometimes bloody, large bubbles predominate, usually on a previously normal skin and only rarely, lesions appear with an ulcer and papules. The new bubbles may be formed in a cluster and around the lesion, similar to what is called "holding the gems".
- Healing may be rapid with hyperpigmentation, but generally without scarring.
- Vesicles and bubbles are mildly itchy, especially above the pelvic area and the mouth.
- The eyes often suffer from burning and itching and scarring rarely exist in the conjunctiva.
Differential diagnosis:
- Streptococcus or bubonic herpes: may resemble the initial lesions of the bubonic bubbly spots, but the short period and response to antibiotics may be useful in differentiation.
- Decomposition of the epidermal epidermis: often since birth and pests when heals leave scarring in the skin and mucous membranes.
- Smooth pigmentation and endocarditis with intestinal dysfunction: Diagnosis may occur, but the onset of bubbles during the first weeks of life in the previous disease and lesions of the mucous membranes of the latter may help to differentiate between the two diseases.
Follicular papillary scarring rarely sores the face and genitals and usually has a short period.
- Pox: rare in children and diagnosis depends on the clinical picture and the manifestations of tissue and immune.
The sputum may show clinical features similar to the bubonic, but the deposition of IgG and C3 in the basal membrane confirms the diagnosis.
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