Scleroderma.. An autoimmune disease characterized by skin thickening due to changes in the connective tissue

Scleroderma:
Connective tissue disease is an autoimmune disease characterized by thickening of the skin due to changes in the connective tissue.
The disease is either topical or only affects the skin and other organs.
Forms of scleroderma:
1 Morphea.
2 Diffuse scleroderma.
3. Lichen sclerosus.
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