Papillon - Lefevre syndrome.. Hyperhidrosis and foul odor. Frequent purulent infections. Dental disease is caused by severe gingivitis. Meningitis calcification

Papillon - Lefevre syndrome:
It is a hereditary disease of infertility, affecting infants and young children.
Clinical manifestations:
Skin manifestations:
Hyperhidrosis may cause smelly.
- Hair is usually natural and may be light and scattered.
- Frequent purulent infections.
- Dental disease caused by severe gingivitis, which may be prone to loss and loss of teeth, especially permanent teeth.
- Dural calcification (Dural) especially in the connection between tent and choroid may be observed in some cases.