Mechanism of the effect of isotretinoin to treat acne .. reduce microbial colony surface and ductal, especially P. acnes fall

Mechanism of Isotretinoin Effect:
1 reduces the secretion of sebum.
2 reduces the colonic bacteria of the surface and ducts, especially the probiotic protons and gradually reduces the interconnections of the ducts.
3 T cells stimulate assistance with subsequent increase in immunoglobulin including "IgE" and reduce chemotaxis.
4 has an effect on germs, corneal cells in the ducts and the formation of inflammation and the formation of glands.
5 affects cell differentiation, possibly as a result of interference with inward vitamin A metabolism.
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