Fanconi's syndrome.. Dark pigmentation or olive brown. Congenital malformations are usually accompanied by bloody abnormalities. Dark hyperpigmentation is generalized, showing smudges in the form of rain drops and a scattered grille

Fanconi's syndrome:
It is a rare hereditary syndrome affecting children, characterized by dark pigment or olive brown, birth defects and usually accompanied by bloody abnormalities.
Clinical manifestations:
The most affected places are bottom trunk, emotion surfaces and neck.
Skin manifestations:
Generalized dark hyperpigmentation. Rainy smudges appear as a grille scattered over dark areas or smudges of darker pigmentation, and are rarely the color of coffee stains with milk.
General features:
The affected child is mentally retarded, cylindrical structure with short and broad hands with fingers attached and pointed, and the thumb may be absent or archaic.
Small head and sexual child (lack of triggers) in addition to some other developmental distortions.
Bloody abnormalities:
Blood changes are anemia, not thrombocytopenia, neutropenia. The lack of mass pellets may lead to death with bleeding and is usually fatal in infants and young children.
There is no increase in the rate of acute bleaching and other growth.
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