Dapsone is an effective drug and should be very careful when used because of the potential for various side effects.
Continuous patient monitoring is very important during treatment due to potential drug toxicity, hemolytic anemia and methemoglobinemia.
Dapsone indications in different skin diseases:
- Pelvic dermatitis.
- Erythema diutinum.
- Spondylosis (falciparum, mucous membranes).
- Chronic bubonic disease in children.
- Pulmonary eruption in systemic lupus erythematosus.
- Parenteral appendicitis.
- Favorable skin pimples.
- Collagen disease such as rheumatoid arthritis.
- Multiple cartilage inflammation.
- Stressed youth pills.
- Conjunctivitis of leukocytes.
- Pelvic granular tumor.
Dapsone Dose:
The initial dose in adults is 50 100 mg / day, and the dose may increase to 400 mg / day depending on the patient's response. The dose that lasts after controlling the disease may be 25 mg / kg.
Some patients can control their condition at lower doses.
Toxicity:
Dapsone toxicity may be a major problem, but it may still have fewer long-term side effects of corticosteroids and sulfapiridine.
The most common side effects are:
- Hemolysis.
- Methemoglobulonemia (hypermethoglobinemia).
- This is also common and responsible for bluish lips.
Regular blood tests to detect hemoglobin, capillaries, leukocytes and thrombocytopenia should be performed in all patients during the first months of treatment with dapsone.
- Destruction of the spinal cord.
Peripheral neuropathy.
- Medicinal rash.
- Renal damage.
- Decrease blood biomein.
- Bile stasis.
- Mental disorders.
- reversible male infertility.
Continuous patient monitoring is very important during treatment due to potential drug toxicity, hemolytic anemia and methemoglobinemia.
Dapsone indications in different skin diseases:
- Pelvic dermatitis.
- Erythema diutinum.
- Spondylosis (falciparum, mucous membranes).
- Chronic bubonic disease in children.
- Pulmonary eruption in systemic lupus erythematosus.
- Parenteral appendicitis.
- Favorable skin pimples.
- Collagen disease such as rheumatoid arthritis.
- Multiple cartilage inflammation.
- Stressed youth pills.
- Conjunctivitis of leukocytes.
- Pelvic granular tumor.
Dapsone Dose:
The initial dose in adults is 50 100 mg / day, and the dose may increase to 400 mg / day depending on the patient's response. The dose that lasts after controlling the disease may be 25 mg / kg.
Some patients can control their condition at lower doses.
Toxicity:
Dapsone toxicity may be a major problem, but it may still have fewer long-term side effects of corticosteroids and sulfapiridine.
The most common side effects are:
- Hemolysis.
- Methemoglobulonemia (hypermethoglobinemia).
- This is also common and responsible for bluish lips.
Regular blood tests to detect hemoglobin, capillaries, leukocytes and thrombocytopenia should be performed in all patients during the first months of treatment with dapsone.
- Destruction of the spinal cord.
Peripheral neuropathy.
- Medicinal rash.
- Renal damage.
- Decrease blood biomein.
- Bile stasis.
- Mental disorders.
- reversible male infertility.
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skin diseases