The first immunoglobulin produced by the body when the neonate is distressed, has acquired an infection or is challenged is.. IgM

The first immunoglobulin produced by the body when the neonate is distressed, has acquired an infection or is challenged is:
a. IgG
b. IgA
c. IgM
d. All of these

Answer C.
Keyword: FIRST IMMUNOGLOBULIN PRODUCED BY THE BODY. Rationale: IgM is the first immunoglobulin produced by the body when the neonate is distressed, has acquired an infection or is challenged. When a newborn is exposed to environmental antigens, production of IgM rapidly increases. This type of immunoglobulin provides protection from gram-negative bacteria. IgM cannot cross the placental barrier.  In cases where large amount of IgM is found in the placenta, possible exposure to infection in the utero is probable.
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