A male client is to receive I.V. vancomycin (Vancocin). When preparing to administer this drug.. vancomycin should be infused over 60 to 90 minutes in a large volume of fluid

A male client is to receive I.V. vancomycin (Vancocin). When preparing to administer this drug, the nurse should keep in mind that:
a.    vancomycin should be infused over 60 to 90 minutes in a large volume of fluid.
b.    vancomycin may cause irreversible neutropenia.
c.    vancomycin should be administered rapidly in a large volume of fluid.
d.    vancomycin should be administered over 1 to 2 minutes as an I.V. bolus.

Answer A.
To avoid a hypotensive reaction from rapid I.V. administration, the nurse should infuse vancomycin slowly, over 60 to 90 minutes, in a large volume of fluid. Although neutropenia may occur in approximately 5% to 10% of clients receiving vancomycin, this adverse effect reverses rapidly when the drug is discontinued.
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