Dr. Santos prescribes glipizide (Glucotrol), an oral antidiabetic agent, for a client with type 2 diabetes mellitus who has been having trouble controlling the blood glucose level through diet and exercise

Dr. Santos prescribes glipizide (Glucotrol), an oral antidiabetic agent, for a client with type 2 diabetes mellitus who has been having trouble controlling the blood glucose level through diet and exercise.
Which medication instruction should the nurse provide?

a- Be sure to take glipizide 30 minutes before meals

b- Glipizide may cause a low serum sodium level, so make sure you have your sodium level checked monthly

c- You won’t need to check your blood glucose level after you start taking glipizide

d- Take glipizide after a meal to prevent heartburn

Answer A.
The client should take glipizide twice a day, 30 minutes before a meal, because food decreases its absorption.
The drug doesn’t cause hyponatremia and therefore doesn’t necessitate monthly serum sodium measurement.
The client must continue to monitor the blood glucose level during glipizide therapy.
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