Which of the following statements is true regarding the Administration of alendronate

Which of the following statements is true regarding the Administration of alendronate?

  • I. Take more than 30 minutes before first food or beverage of the day
  • II. Take with 6 to 8 ounces of plain water
  • III. Remain fully upright ( sitting or standing ) for about 30 minutes
  • A. I only
  • B. III only
  • C. I and II only
  • D. II and III only
  • E. I, II and III

The correct answer is E. I, II, and III.

Here's why:

I. Take more than 30 minutes before first food or beverage of the day:

This is true. Alendronate needs to be taken on an empty stomach, at least 30 minutes before the first food or beverage of the day (except plain water). Eating or drinking anything else can reduce the absorption of the medication and make it less effective.

II. Take with 6 to 8 ounces of plain water:

This is also true. Alendronate should be taken with a full glass of plain water (6 to 8 ounces) to help it travel down the esophagus and reduce the risk of esophageal irritation.

III. Remain fully upright (sitting or standing) for about 30 minutes:

This is also true. After taking alendronate, it's important to remain fully upright (sitting or standing) for at least 30 minutes and avoid lying down. This helps prevent the medication from irritating the esophagus.
Therefore, all three statements are true regarding the administration of alendronate.
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