Typical features of conventional osteosarcoma does not include.. Increased activity in the blood pool phase of an isotope bone scan

Typical features of conventional osteosarcoma does not include:
A- Epiphyseal involvement… False (Metaphesis)
B- Metastatic spread via the haematogenous root. True
C- Increased activity in the blood pool phase of an isotope bone scan. True
D- Peak incidence between 10 and 20 years of age. True
E- Periosteal reaction. True
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