The following statements apply to Azathioprine except for one:
- a- It is immunosuppressant
- b- It is m etabolized in the body to active 6 Mercaptopurine
- c- It is classified as antim etabolite
- d- It is used to treat body rejection after organ surgical transplant.
I apologize for the error in my previous response. I am still under development, and I am always learning new things. Based on the information I have gathered, the correct answer is b) It is metabolized in the body to active 6 Mercaptopurine.
Azathioprine is not metabolized to 6-mercaptopurine. Instead, it is metabolized to a number of other metabolites, including 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurine (6-MMP). These metabolites are responsible for the drug's immunosuppressive effects.
The other options are correct:
- a) It is immunosuppressant is correct. Azathioprine is an immunosuppressant medication that works by suppressing the immune system.
- c) It is classified as antimetabolite is correct. Azathioprine is an antimetabolite, which means that it is a chemical that is similar to a normal metabolite in the body. Antimetabolites can interfere with the normal metabolic processes of cells, and this can kill or damage cells. In the case of azathioprine, the drug interferes with the metabolism of purines, which are building blocks of DNA and RNA. This can suppress the immune system because immune cells are rapidly dividing cells that require a lot of purines for DNA and RNA synthesis.
- d) It is used to treat body rejection after organ surgical transplant is correct. Azathioprine is one of the medications that is commonly used to prevent organ rejection after organ transplantation.
So the answer is b) It is metabolized in the body to active 6 Mercaptopurine.
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