Sibutramine should not be used in patients:
- l. With a body mass index greater than 30 kg/m2
- ll. Taking MAO inhibitors
- lll. With poorly controlled hypertension
- A. l only
- B. lll only
- C. l and ll only
- D. ll and lll only
- E. l , ll and lll
The correct answer is E. l , ll and lll.
Sibutramine is a medication that was used to treat obesity. However, it was withdrawn from the market in 2010 due to an increased risk of cardiovascular events, such as heart attack and stroke.
Sibutramine should not be used in patients who meet any of the following criteria:
- Body mass index (BMI) greater than 30 kg/m2:
Sibutramine was only approved for use in patients with a BMI of 30 kg/m2 or greater.
- Taking monoamine oxidase inhibitors (MAOIs):
MAOIs are a type of medication that is used to treat depression and other mental health conditions. Sibutramine can interact with MAOIs and cause serious side effects, including increased risk of seizures.
- Poorly controlled hypertension:
Hypertension, or high blood pressure, is a risk factor for cardiovascular events. Sibutramine can increase blood pressure, so it should not be used in patients with poorly controlled hypertension.
Therefore, the answer is E. l , ll and lll. Sibutramine should not be used in patients who meet any of these criteria.
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Pharma