Concerning multiple myeloma.. Lytic lesions in bone are well defined. The axial skeleton is predominantly involved

Concerning multiple myeloma:
A- Doesn't develop from a solitary plasmacytoma. False (1/3 of  plasmacytomaMM)
B- 75% of patients are aged over 50Y. False (95% of cases are over 40y)
C- The axial skeleton is predominantly involved. True
D- Lytic lesions in bone are well defined. True
E- It commonly presents as generalized osteosclerosis. False
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