Causes of rheumatoid arthritis.. Mikopktiria. Synergies between environmental factors and genetic factors. The impact of the genetic factor

The main reason for the occurrence of (RA ) Is not clear so far, although there is evidence to suggest (RA) Is an immune-mediated disease, it is not clear if the self-immune disease primarily. Possible that there will be many factors that do the immune response in people at risk of whether these factors inflammation or self-antigen or environmental factors, but this has not been proven so far. There are studies in epidemiology supports that there is a synergy between environmental factors and genetic factors to cause disease (RA ). Studies conducted on twins suggests that the impact of the genetic factor does not exceed 30%.
Esteban Barr virus has been linked to RA For about 10 years about 80% of patients with RA To have antibodies directed against antigens private the Esteban-Barr virus as the virus Parvo virus The particular type B19 Has been linked to RA In addition to mico bacteria.
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