Clinical association of a antibodies. B. A with other autoantibodies.. Recurrent spontaneous abortion and fetal mortality and arterial and venous thrombosis

Clinical association of antibodies APA
N APA antibodies Linked to several conditions including recurrent spontaneous abortion and fetal mortality and arterial and venous thrombosis, that patients who have levels of these antibodies branded as infected antibodies APA syndrome APA syndrome.
Although described many antibodies APA Non That two of them are most relevant to spontaneous abortion and described well, one of the class IgG And be of substandard medium Oomtfh both ACA AndLA.
It is also one of the markers of this syndrome.
The IgG antibodies And to a lesser extent IgM Is closely related antibodies APA syndrome , Either antibody IgA Did not receive the same amount of attention.
Modern Chirdrasat to link antibody IgA With thrombotic events in Rthwaih disease.
 Rheumatic diseases Had suggested To link antibodies APA IgA class And more particularly antibodies ACA And B 2 GP 1 Including frequent cases of spontaneous abortion and cases embryos Garmarovh death causes and where the results of tests on deduced IgG And LA Negative, Which refers to the possibility of adopting ACA antibodies IgA class In the diagnosis of antibody syndrome APA And that no usual diagnosed modalities.
So Valahmah clinical antibodies LA Or high levels of antibodies ACA Been increasingly apart in a number of clinical disorders including SLE And other immune diseases and connective tissue disorders disordersConnective tissue Caused by some treatments and some disorders not related Pal SLE, Disorderly nervous system and eye infections or eating certain drugs.
The presence of antibodies APA In some cases is extra Epiphenomenon phenomenon While be directly related and essential in other cases.
The clinical signs included inflammatory thrombophlebitisThrombophlebitis Variety called syndrome antibodies LA And antibody syndrome phosphorous lipids and protein antibody syndrome APA.
The majority of women with antibodies APA Do not have symptoms phenomenon is that some of them have to have immunity to diseases which requires assessing their cases in an appropriate manner.
Despite the presence of antibodies APA High in SLE ​​patients, Guerin There Another satisfactory events have making your diagnosis Palmarbat who have thrombotic events the presence of antibodies to APAPoints out that there is antibody syndrome APA Primary Primary APA syndrome.
PayPal feature women with SLE Petkrarhadduth spontaneous abortion, Guerin women who have abortions spontaneously to Ateltaki with indicators laboratory diagnostics SLE.
ANA antibodies play And LA ACA causing role in the frequent occurrence of spontaneous abortion self malady Idiopathic And there is a need to deal with these problems and treated on the basis of these indicators laboratory.
Studies indicated frequency of spontaneous abortion in women who reveal their rise in antibodies ANACompared with women Giralmjhiat.
Final did not specify the reasons behind the formation of such opposites but it seems that there is a willingness and genetically, as may be determined in the light of the pattern of HLA.
The SLE Model is a disease that accompanies his presence antibodies APA Which cause significantly higher rates of spontaneous abortion, including nearly 50% of women living with the disease in its active form.
Women who get to have spontaneous abortions frequently does not apply to them PAL standards SLE Guerin and many of them reveal their features like lupus lupus likeActivation and features multi monoclonal B lymphoma cells 
B-lymphpcytes Be more common to have.
The exact mechanism through which contribute ANA antibodies In causing spontaneous abortion Giroadhh enough Guerin pathological studies on Almchaam showed inflammatory changes in the uterus with a vascular inflammation.
Test is used to detect antibodies ANA To investigate incidence of SLE disease And other diseases, such as rheumatic fever Rheumatic fever And rheumatoid arthritis Rheumatoid arthritis, Collected all these diseases common clinical features, as is arthritis Arthritis The common denominator among them, as are all characterized by producing antibodies Alztah.
Found that antibodies ANA Is Kama Gljubljn interacts with the nuclei of cells of various organs and it belongs to more than one class of varieties immune Algljubljnat and undetectable ELISA technology As factors are detected antibodies nuclear protein shapes pain accompanied with some immune diseases.
Not all antibodies ANA Satisfactory for the adoption of pathogenicity class specific immunoglobulins and immune complex consisting size and location of the deposition tissue and its ability to install the system complement Complement system.
There are other autoantibodies such as antibodies AMA Where Istaan ​​these antibodies to detect proteins, lipids phosphorous located within the inner membrane of mitochondria Mitochondria EspeciallyCL.
Antibodies AMA level rises In the case of SLE And thyroid disease, rheumatoid arthritis and pernicious anemia etc.
As for Boddad Anti-dsDNA The people there are three types of antibodies directed against DNA, namely:
1. Anti-ssDNA antibodies
2. Anti-dsDNA antibodies
3. Hybrid antibodies both unilateral and bilateral. In time by which antibodies indicates 
Anti-dsDNA PayPal to injury SLE Van Anti-ssDNA antibodies May be associated with many chronic conditions.
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